The NeuroKCNQpathies consortium is made up of 8 independent
research groups from across Europe each with an interest in a distinct aspect of
KCNQ Channels. However, the overlap in the interests of each group permits us to
establish a direct link from the molecular and structural biology of these channels
through to their pharmacology.

The very nature of the consortium reflects the multidisciplinary
approach that will be taken to address all aspects of these channels, from the fundamental
structural and cellular changes produced by the genetic changes in KCNQ channels, to the
design of drugs that might help in redressing or alleviating the problems that are generated.
It would be nearsighted to consider that benefit of our efforts will only be
seen in the advance in our understanding of the function and dysfunction of these channels.
We also hope to advance efforts directed at designing possible therapeutic approaches to benefit
those suffering from such conditions. Furthermore, our efforts should enhance the availability of
diagnostic and preventative tools.
Finally, we believe that the results generated in this project will not be
restricted in their application to monogenic neurological KCNQ disorders alone. It is clear
that they may have a bearing in far more extended areas.